These results suggest that the calcium alginate tested may improve some cellular aspects of normal wound healing, but not others.
One study considered two treatment protocols for the management of patients with non-infected cavity wounds, using data obtained from both the community and the outpatients clinic.For shallow, heavily exuding wounds such as leg ulcers, fibrous sheet dressings made from alginate fibre may be used, while cavity wounds, traditionally packed with gauze soaked in saline, hypochlorite, or proflavine, are now more commonly dressed with alginate fibre in the form of ribbon or rope.For epithelizing wounds, alginates have an advantage over cellulose dressings in that they can be removed without causing pain or trauma if they are first well soaked with sodium chloride solution.Therefore, silver-containing hydrofiber dressings may offer an effective adjunct in the treatment of patients with pemphigus vulgaris with extensive skin involvement.Our encouraging experience with these dressing patches may be extended to manage other large exudation wounds.Wound fluid spread laterally onto surrounding normal skin by about 40% more with Sorbsan than with the other alginate dressings after 24h (P = 0.026).
The corresponding figure after 66h was 20% (P = 0.030).
The authors suggest that alginates should be reserved for problematic haemorrhage and be removed from the tooth socket soon after haemostasis .
To date, this is the only published report concerning foreign body reaction to alginate.
Alginate fibres trapped in a wound are readily biodegraded .
Alginate dressings maintain a physiologically moist microenvironment that promotes healing and the formation of granulation tissue.
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